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ISSN 2278-2540 | DOI: 10.51583/IJLTEMAS | Volume XV, Issue VI, June 2026
Using ICA Neuroimaging Techniques to Detect Neurological
Abnormalities.
Smt. Preethi.Warrier
M.E .Electronics(Dig Systems) Shah and Anchor Kutchhi Engineering College
DOI: https://doi.org/10.51583/IJLTEMAS.2026.150600154
Received: 28 June 2026; Accepted: 07 July 2026; Published: 18 July 2026
ABSTRACT
EEG (Electroencephalogram) measures electrical potentials on the scalp surface that occur as a result of dynamic
brain function. This paper presents the method to extract EEG Data and various methods used to perform EEG
Neuroanalysis, and why the author has chosen to work on ICA method. EEG data is collected by placing sensors
on a person’s scalp at different positions, amplifying data by 100db, digitizing it with a sampling rate of 256HZ
and using BLUETOOTH Technology to wirelessly transmit it to the computer. EEGLAB, a C library and tool
integrated in MATLAB, has been described. The methodology used to obtain the EEG datasets and implement
both ICA methods on the data has been presented. Baseline wander and power line interference were also
removed from baseline wander and power line interference from the EEG data. The time taken for ICA and
FAST ICA has been compared. Finally, neurological abnormalities were detected abnormalities in brain, using
ICA, by detecting spikes and sharp waves in EEG.
Keywords:
EEGLAB, ICA, Artifacts, Whitening, Sphering
INTRODUCTION
EEG (Electroencephalography) 1 measures electrical potentials on the scalp surface that occur as a result
of dynamic brain function. The procedure involves placing multiple sensors on the scalp. These sensors
have the ability to measure potential changes with microvolt sensitivity.
One challenge of using scalp-based data is that each sensor is actually measuring surface potential changes
caused by a superposition of underlying signals from various sources within the brain, as well as extra
brain sources. These signals are transmitted to the scalp via volume conduction through various tissue and
bone structures. Each sensor is actually receiving a mixture of different signals, and a given EEG signal is
obtained from sensors, and at different intensities.
The hardware used, does introduce some power line interference in the EEG waveforms. Also, one neuron
in brain does not influence 1 sensor, but many sensors at a time, so channel data are dependent on each
other. Infomax and Fast ICA, mathematically remove these problems.
The signal mixtures at each sensor can be separated into several independent components. Some of these
will correspond to artifacts such as eye blinks, heartbeats and in some cases, the experimental apparatus.
Independent Component Analysis (ICA) is a mathematical technique for extracting components, where
the extracted components describe temporally independent activities from spatially fixed overlapping
sources. Sources corresponding to artifacts can then be removed from the signal mixtures to facilitate
further analysis of the EEG data.
The big advantage of using ICA over other methods is that, it helps in parallelizing the analysis, that is,
individually, neuroanalysts can analyse individual channel, as each channel is independent of each other.
By combining the high-resolution data provided by dense- array EEG with sophisticated data analysis
techniques such as ICA, researchers are developing ways to ‘see’ into the neurophysiological and
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cognitive processes within the brain. Section 2 describes the methods used to extract the EEG signal s
from the brain and display EEG on computer. Component Analysis. Section 3 shows a table of 22
channels. Section 4 shows the block diagram and work done by the author. Section 6 describes the
software to be used. Section 7 describes what are the signs of brain abnormalities, and how they are
detected using ICA methods. Section 8 describes the applications and future scope.
EEG data extraction
In conventional scalp EEG, the recording is obtained by placing electrodes on the scalp with a conductive
gel or paste, usually after preparing the scalp area by light abrasion to reduce impedance due to dead skin
cells.The sensor is known as ENOBIO.Some systems use caps or nets into which electrodes are
embedded; this is particularly common when high-density arrays of electrodes are needed.Each electrode
is connected to one input of a differential amplifier (one amplifier per pair of electrodes); a common
system reference electrode is connected to the other input of each differential amplifier.
The amplification is about 1,000100,000 times, or 60100 dB of voltage gain. Most EEG systems ever,
are digital, and the amplified signal is digitized via an analog-to-digital converter, after being passed
through an anti-aliasing filter. Analog-to-digital sampling typically occurs at 256-512 HZ in clinical scalp
EEG; TI-MSP 430 is the processor used for digital conversion and filtering. The digital EEG signal is stored
electronically and can be filtered for display. Typical settings for the high-pass filter and a low-pass filter
are 0.5-1 HZ and 3570 HZ, respectively. The high-pass filter typically filters out slow artifact, such as
electrogalvanic signals and movement artifact, whereas the low-pass filter filters out high- frequency
artifacts, such as electromyographic signals. An additional notch filter is typically used to remove artifact
caused by electrical power lines (60 HZ in the United States .This EEG data is then transmitted wirelessly
to a computer,using BLUETOOTH Technology. A typical adult human EEG signal is about 10µ V to 100
µV in amplitude when measured from the scalp and is about 10 20 mV when measured on computer.
Fig.1.Figure shows the extraction and Wireless transmission of EEG
ICA (Independent Component Analysis)
Initially, EEG Neuroimaging was performed using clustering methods. Now, clustering could not handle
large datasets, and also, the individual channel data was dependant on each other.
Cross Validation method, divided he data into 2 subsets, and the 2 subsets were independent of each other,
but this method too was very time taking.
Independent Component Analysis (ICA)[2] is a mathematical technique for extracting components, where
the extracted components describe temporally independent activities from spatially fixed overlapping
sources. Sources corresponding to artifacts can then be removed from the signal mixtures to facilitate
further analysis of the EEG data.
One form of ICA is encapsulated in the both ICA methods, first described in and implemented in
MATLAB. FastICA works by searching for a weight matrix that maximizes the non-gaussianity of the
resultant components[4]. Any mixture of non-gaussian random variables will be more gaussian than the
variables themselves (Central Limit Theorem of Statistics). Therefore, it is possible to use non-gaussianity
as a measure of statistical independence.
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The phases of execution of FAST ICA are:
Start processes on head and remote nodes
1.
Load parameters and replicate to workers
2.
Load data and distribute amongst workers
3.
Optionally whiten the data
4.
Load parameters and replicate to workers
5.
Output components, weights, sphering matrix
Channels Used in ICA
For the first study, on the applicability of ICA on electroencephalogram, the EEG consists of 22 signals,
recorded by unipolar electrodes at a sampling rate of 250Hz[5].
For the second part of the study the polysomnographic data used in the study were collected at the
Asklepios Clinic, Gauting, Munich, Germany. The sampling rates of the channels are presented below.
Signal
Unit
Sampling
Freq.
EEG --- C4/A1
µV
125 Hz
EEG --- C3/A2
µV
125 Hz
EOG RIGHT
F4/A1
µV
125 Hz
BODYPOS
HANDY F3/A2
''
125 Hz
EMG CHIN P4/P3
µV
250 Hz
ECG --- Ecg
µV
125 Hz
RESP FLOW Fp2/Cz
''
25 Hz
RESP FLOW Fp1/Cz
''
25 Hz
RESP FLOW Fz/Cz
''
25 Hz
RESP THORAX Thrx
µV
25 Hz
RESP ABDOMEN Abdm
µV
25 Hz
SOUND RAW Snd
µV
250 Hz
SAO2 SCHWARZ Oxi
%
25 Hz
EMG TIBIALR T4/T6
µV
250 Hz
EMG TIBIALL T3/T5
µV
250 Hz
BODYPOS SCHWARZ Pos
''
25 Hz
CPAP SCHWARZ Prss
mBa
25 Hz
TABLE 1: 22 Eeg Channels
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Work Done
Proposed Block Diagram
Fig.2.Block Diagram
Objective of Work
The objective of work is to collect EEG reports and use Infomax and Fast ICA methods for analyzing a
large set of EEG data samples and separate most mixed components that explain the observed data. The
reduction in execution time provided by Fast ICA was one of the primary motivators for this research.
Also, raw EEG data, which looks similar for all persons, is analyzed using both methods, and a better
output is obtained which shows abnormalities clearly.
Proposed Experimental Work
The tasks of ICA are:
1.
Obtain input data, in the form of a matrix x.
2.
Search for a weight matrix W such that will unmix the whitened signal mixtures x into a set of
independent source signals s.
3.
Compute covariance matrix, sphering matrix, to make data uncorrelated with each other.
4.
Apply the transfer Functions to an Inverse system, to obtain the reconstructed sensor signals.
Infomax uses Linear Transformation methods, where the direction of data vectors, and the angle between
the previous and new weights, is taken for calculation. Fast ICA is a fixed point algorithm, which involves
simple matrix operations, thus making it faster than infomax. Depending upon the configurations of the
system, Fast Ica takes less than half the time taken by Fast ICA.
The execution time of both methods was measured after implementing them, and proved that, Fast ICA is faster.
But, in some cases, after observing the waveforms produced by both methods, Infomax output looks more
accurate than Fast ICA.
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Software Design
MATLAB programs were developed for both Infomax and Fast ICA , using commands in MATLAB. Using
tic and toc commands, the time taken for analyzing has been calculated. Also, the codes for removing baseline
wander and power line interference, have been developed in MATLAB. Using MATLAB plot and subplot
commands, individual patient’s data can be observed. 325 patients’ data is uploaded on MATLAB directory.
EEGLAB[3] is a Matlab toolbox distributed under the free GNU GPL license for processing data from
electroencephalography(EEG), magnetoencephalography MEG and other electrophysiological device.
Along with all the basic processing tools, EEGLAB implements independent component analysis (ICA),
time/frequency analysis, artifact rejection, and several modes of data visualization. EEGLAB allows
users to import their electrophysiological data in about 20 binary file format from standard EEG
manufacturer, preprocess it, visualize activity in single trials, and perform ICA. Artifactual ICA
components may be subtracted from the data. Alternatively, ICA components representing brain activity
may be further processed and analyzed. EEGLAB also allow users to group data from several subjects,
and to cluster their independent components. EEGLAB may be downloaded at
http://sccn.ucsd.edu/eeglab.
MATLAB programs were developed for both Infomax and Fast ICA , using commands in MATLAB.
Detection of Abnormalities.
ICA extracts the independent components from the data and makes it artifact free. Soon, the raw data,
which looks similar for most persons, looks accurate and proper for each patient.
Spikes and Sharp waves are the main indications of any abnormality. The presence of spikes indicates
the presence of idiopathic (primary) epilepsy in a patient. The presence of sharp waves indicates that the
patient is suffering from Symptomatic epilepsy, which is not genetic.
Spikes are narrow waves with high amplitude. Their sudden occurrence in an otherwise smooth EEG
waveform indicates that the person is abnormal.
Sharp waves are broader waves, with negative amplitude; they also indicate that the person is suffering
from epilepsy.
Likewise, using the frequency of occurrence of spikes and sharp waves, a person’s neurological condition
can be detected.
Applications
ICA is a mathematical technique for extracting independent components. Sources corresponding to
artifacts are then removed from the signal mixtures to facilitate further analysis of the EEG data. So, the
ways to observe the neurophysiological processes within the brain become simple because of ICA.
Fast ICA provides a significant advantage over the existing MATLAB-based algorithms in two ways:
execution time and data size. The reduction in wall-clock time provided by ICA was one of the primary
motivators for the ICA research. However, an equally significant feature of ICA is its ability to handle
much larger data sets than MATLAB can handle.
Work Done and Results
EEG data from 325 patients were collected from [6].This has been loaded on MATLAB directory, for further
processing. The data consists of 2500 columns, that is, the number of samples. Also,
The data were subdivided the entire data into 6 subplots, for the important 6 channels, and represented them.
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Each patient’s independent data can be observed. Also, baseline wander and power line interference has been
removed.
The execution time of both algorithms was measured. The average execution time of Infomax ICA was 2.18 s,
whereas FastICA required 0.53 s, corresponding to a computational speedup of approximately 4.1×. FastICA
therefore provided substantially faster execution while preserving effective component separation. The
processed EEG signals were further analyzed to identify epileptic abnormalities based on spikes and sharp
waves.
Also, the author has worked on detecting the type of epilepsy that some patients are suffering from, by
observing the pattern of spikes and sharp waves.
CONCLUSION
The ICA class of techniques and parallel implementations of FAST ICA Algorithm and INFOMAX has
been described by the author. Indeed, one active area of neuroscience research is the comparison of
different ICA algorithms as applied to EEG. Different algorithms are appropriate for different assumptions
about the EEG data and the underlying signals.
INFOMAX uses fractional values for the whitening and sphering matrices. FAST ICA uses only decimal
values, which makes computations easy, and less time taking, but the resolution is little reduced.
It is being planned to increase the usability of HiPerSAT by increasing the performance of the existing
algorithms, and by implementing additional ICA methods.
Also, to make online extraction of EEG possible, the author are working on coding the programs in TURBO
C, C++
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