Donor-Funded HIV Programs in Nigeria: Progress, Systemic Gaps, and Sustainability Pathways from a Health Systems and Financing Perspective (2018–2025)
Authors
Lukman Ademola Adepoju
Department of Medical Laboratory, University of Lagos, Lagos Nigeria (NG)
Oyetunji Oyewale
Department of Medical Laboratory Science, Ladoke Akintola University of Technology, Ogbomosho, Nigeria. (NG)
Odekunle Bola Odegbemi
Medical Laboratory Science Department, Edo State University, Uzairue, Edo State, Nigeria. (NG)
Ifeoluwa Abraham Adeagbo
Department of Medical Laboratory Science, Ladoke Akintola University of Technology, Ogbomosho, Nigeria. (NG)
Elizabeth Oladipo
Department of Medical Laboratory Science, Ladoke Akintola University of Technology, Ogbomosho, Nigeria. (NG)
Article Information
DOI: 10.51583/IJLTEMAS.2026.150100021
Subject Category: Public health
Volume/Issue: 15/1 | Page No: 275-285
Publication Timeline
Submitted: 2026-01-27
Published: 2026-01-27
Abstract
Over 40 years after the identification of human immunodeficiency virus (HIV), Nigeria remain one of the highest burdens of HIV infections in the world, accounting for almost 10% of new infections in sub-Saharan Africa. Despite significant investments and technical supports from different foreign donors including the United States President’s Emergency Plan for AIDS Relief (PEPFAR), the Global Fund, and bilateral partners. The persistent structural, financial, and programmatic gaps continue to hamper the country’s HIV response. This assessment of HIV-related interventions in Nigeria examines what has been achieved, what still need to be done, and how to establish a sustainable and domestically owned HIV care. The review summarizes evidence from peer-reviewed literature (2018–2025) and major institutional reports (UNAIDS, NACA, WHO, PEPFAR) to assess five key domains: coverage and access, funding and sustainability, health system strengthening, monitoring and evaluation, and sociocultural barriers. Evidence shows that while substantial progress has been achieved in testing, antiretroviral therapy (ART) coverage, and community-based care, the HIV response remains heavily donor-dependent, urban-centered, and fragmented across vertical program streams. The review concludes that to achieve long-term epidemic control (EC) and universal health coverage (UHC) in Nigeria’s HIV care and programming with there is a need for domestic financing, health system integration, decentralized service delivery, and data-driven accountability frameworks.
Keywords
HIV, Nigeria, donor funding, PEPFAR, Global Fund, sustainability, health systems, intervention gaps, policy reform
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References
1. Adebayo, S. B., Uthman, O. A., Wiysonge, C. S., Stern, E. A., Lamont, K. T., & Ataguba, J. E. (2022). Health system constraints and sustainability challenges of HIV programmes in Nigeria: A mixed-methods analysis. BMC Health Services Research, 22, 1234. https://doi.org/10.1186/s12913-022-08123-9 [Google Scholar] [Crossref]
2. Ali, G. S., Ogwuche, A. O., Entonu, A. I., & Durowade, A. K. (2025). Stigma, Discrimination and Associated Determinants Among People Living With Hiv/aids Accessing Anti-retroviral Therapy in Ikeja, Lagos State, Nigeria. [Google Scholar] [Crossref]
3. Boakye, D. S., Kumah, E., & Adjorlolo, S. (2024). The fight for an AIDS-free world: confronting the stigma, reaching the marginalized. Annals of Global Health, 90(1). [Google Scholar] [Crossref]
4. Centers for Disease Control and Prevention (CDC) Nigeria. (2022). HIV Monitoring and Evaluation System Assessment Report. Abuja: CDC Nigeria. [Google Scholar] [Crossref]
5. Chizoba, A. F., Adogu, P. O. U., & Chineke, H. N. (2020). A review to identify the gaps in prevention of mother to child transmission of HIV Services in Nigeria. Journal of Scientific Research and Reports, 26(8), 67-78. [Google Scholar] [Crossref]
6. Dzinamarira, T., Rwibasira, G., Mwila, L., Moyo, E., Mangoya, D., Moyo, P., ... & Muvunyi, C. M. (2025, January). Advancing Sustainable HIV Services Through Integration in Primary Healthcare in Sub-Saharan Africa: A Perspective on Practical Recommendations. In Healthcare (Vol. 13, No. 2, p. 192). MDPI. [Google Scholar] [Crossref]
7. Elendu, C., Amaechi, D. C., Elendu, T. C., Amaechi, E. C., Elendu, I. D., Akpa, K. N., ... & Idowu, O. F. (2025). Shaping sustainable paths for HIV/AIDS funding: a review and reminder. Annals of Medicine and Surgery, 87(3), 1415-1445. [Google Scholar] [Crossref]
8. Emmanuel, G. O., Sanni, O. F., Roger, A., Umoh, P., Boniface, O. B., Paul, A., ... & Auwal, A. M. (2025). Improving HIV Prevention for Key Populations in Nigeria: Insights on Access, Barriers, Stigma, and Service Utilization. International Journal of Maternal and Child Health and AIDS, 14, e005. [Google Scholar] [Crossref]
9. Federal Ministry of Health (FMoH). (2023). National HIV/AIDS Progress Report. Abuja: FMoH. [Google Scholar] [Crossref]
10. Global Fund. (2024). Nigeria Grant Performance Update. Geneva: The Global Fund to Fight AIDS, TB and Malaria. [Google Scholar] [Crossref]
11. Goldstein, D., Salvatore, M., Ferris, R., Phelps, B. R., & Minior, T. (2023). Integrating global HIV services with primary health care: a key step in sustainable HIV epidemic control. The Lancet Global Health, 11(7), e1120-e1124. [Google Scholar] [Crossref]
12. Ibiloye, O. (2024). Realist evaluation of a community-based antiretroviral therapy programme for key populations in Nigeria (Doctoral dissertation, University of Antwerp). [Google Scholar] [Crossref]
13. Joint United Nations Programme on HIV/AIDS. (2024). AIDS, crisis and power to transform (Text extract): UNAIDS global AIDS update 2025 (Executive Summary). Infectious Diseases & Immunity, 10-1097. [Google Scholar] [Crossref]
14. Makwara, T., Maramwidze, E., & Stephen, M. (2024). Leveraging Technology in Small Businesses’ Corporate Social Responsibility Activities Addressing HIV/AIDS Issues in Developing Countries: A Theoretical Study. Emerging Perspectives on Society, Health, and Economics in Sub-Saharan Africa, 39. [Google Scholar] [Crossref]
15. Marqusee, H., Schowen, R., Amanzi, P., Baker, S., Egena, P., Hijazi, M., ... & Pius, J. (2024). Engaging the private sector to increase access to HIV services and increase sustainability of the HIV response. BMC Health Services Research, 24(Suppl 1), 1672. [Google Scholar] [Crossref]
16. Mwango, L. K., Stafford, K. A., Blanco, N. C., Lavoie, M. C., Mujansi, M., Nyirongo, N., ... & Claassen, C. W. (2020). Index and targeted community‐based testing to optimize HIV case finding and ART linkage among men in Zambia. Journal of the International AIDS Society, 23, e25520. [Google Scholar] [Crossref]
17. National Agency for the Control of AIDS. (2022). Revised national HIV/AIDS strategic framework monitoring and evaluation plan. Government of the Federal Republic of Nigeria. https://naca.gov.ng/ [Google Scholar] [Crossref]
18. National Agency for the Control of AIDS. (2023). Revised national HIV/AIDS strategic framework: Financing and sustainability analysis. Government of the Federal Republic of Nigeria. https://naca.gov.ng/national-hiv-aids-strategic-framework/ [Google Scholar] [Crossref]
19. Nigeria Health Watch. (2024). Sustaining Nigeria’s HIV response amid declining donor funding. Nigeria Health Watch. https://nigeriahealthwatch.com/sustaining-nigerias-hiv-response-amid-declining-donor-funding/ [Google Scholar] [Crossref]
20. Njoka, P. M. (2015). Factors influencing utilization of routine health data in evidence based decision making in Hiv/Aids services by public health facilities in Nakuru county (Doctoral dissertation, University of Nairobi). [Google Scholar] [Crossref]
21. Odimegwu, C. O., Akinyemi, J. O., & Alabi, O. O. (2017). HIV‐Stigma in Nigeria: Review of Research Studies, Policies, and Programmes. AIDS research and treatment, 2017(1), 5812650. [Google Scholar] [Crossref]
22. Ogbuabor, D., Olwande, C., Semini, I., Onwujekwe, O., Olaifa, Y., & Ukanwa, C. (2023). Stakeholders’ perspectives on the financial sustainability of the HIV response in Nigeria: a qualitative study. Global Health: Science and Practice, 11(2). [Google Scholar] [Crossref]
23. Ogundeko-Olugbami, O., Ogundeko, O., Lawan, M., & Foster, E. (2025). Harnessing data for impact: Transforming public health interventions through evidence-based decision-making. World Journal of Advanced Research and Reviews, 25(1), 2085-2103. [Google Scholar] [Crossref]
24. Olakunde, B. O., & Ndukwe, C. D. (2015). Improved domestic funding enhances the sustainability of HIV/AIDS response in Nigeria. Annals of global health, 81(5), 684-688. [Google Scholar] [Crossref]
25. Part, B. (2025). HIV Response Sustainability Roadmap. [Google Scholar] [Crossref]
26. PEPFAR. (2023). Nigeria Country Operational Plan (COP 2023). Washington DC: US Department of State. [Google Scholar] [Crossref]
27. Stangl, A. L., Pliakas, T., Izazola-Licea, J. A., Ayala, G., Beattie, T. S., Ferguson, L., ... & Bendaud, V. (2022). Removing the societal and legal impediments to the HIV response: An evidence-based framework for 2025 and beyond. PloS one, 17(2), e0264249. [Google Scholar] [Crossref]
28. The Global Fund to Fight AIDS, Tuberculosis and Malaria. (2024). Nigeria: Investment landscape and results. https://www.theglobalfund.org/en/portfolio/country/nigeria/ [Google Scholar] [Crossref]
29. U.S. President’s Emergency Plan for AIDS Relief. (2023). PEPFAR 2023 annual report to Congress. U.S. Department of State. https://www.state.gov/pepfar-annual-report/ [Google Scholar] [Crossref]
30. Umar, M. L. (2021). Evaluation of Integrated HIV/AIDS and Primary Health Care Services in Northern Nigeria (Doctoral dissertation, University of Sheffield). [Google Scholar] [Crossref]
31. UNAIDS. (2023). Country factsheet: Nigeria — HIV and AIDS estimates. Joint United Nations Programme on HIV/AIDS. https://www.unaids.org/en/regionscountries/countries/nigeria [Google Scholar] [Crossref]
32. UNAIDS. (2024). UNAIDS Global AIDS Update 2024: The Urgency of Now: AIDS at a Crossroads. Stylus Publishing, LLC. [Google Scholar] [Crossref]
33. UNICEF. (2024). Annual PMTCT and Paediatric HIV Progress Report – Nigeria. New York: UNICEF. [Google Scholar] [Crossref]
34. World Health Organization. (2023). Consolidated HIV, viral hepatitis and STI guidelines: Programmatic and health-systems considerations. World Health Organization. [Google Scholar] [Crossref]
35. https://www.who.int/publications/i/item/9789240052178 [Google Scholar] [Crossref]
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