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Seroprevalence of Hepatitis E Virus Among Patients Attending Federal Medical Centre, Mubi, Adamawa State, Nigeria.

Authors

Papka I. M

Department of Microbiology, Faculty of Science, Adamawa State University, Mubi, PMB 25, Adamawa state, Nigeria. (NG)

Umar M. M

Department of Environmental Health Science, Bayero University, Kano. Nigeria (NG)

Ishaq M. S

Galtima mai Kyari College of Health Sciences and Technology Nguru, Yobe State. Nigeria. (NG)

Damijida J

Department of Microbiology, Faculty of Science, Adamawa State University, Mubi, PMB 25, Adamawa state, Nigeria. (NG)

Article Information

DOI: 10.51583/IJLTEMAS.2026.150400033

Subject Category: Microbiology

Volume/Issue: 15/4 | Page No: 371-380

Publication Timeline

Submitted: 2026-05-04

Published: 2026-05-04

Abstract

Hepatitis E virus (HEV) is an emerging cause of acute viral hepatitis, particularly in regions with poor sanitation. This study assessed the seroprevalence of HEV among patients attending the Federal Medical Centre (FMC), Mubi, Nigeria. Methods: A cross-sectional study involving 100 consenting participants was conducted. Blood samples were analyzed for HEV antibodies using standard serological methods. Demographic data and HEV seroprevalence were analyzed and presented in tables and figures. Results: Out of the 100 participants, 28 (28%) were male and 72 (72%) female, with a mean age of 36.40 ± 13.20 years. Overall, 6 (6%) tested positive for HEV antibodies, while 94 (94%) were negative. HEV seroprevalence among females was 4 (83%) and 1 (17%) among males. However, the difference was not statistically significant (p = 0.98). The majority of participants were HEV-negative, suggesting low-level circulation of the virus in this population. Conclusion: The study found a moderate HEV seroprevalence (6%) among patients at FMC, Mubi. These findings highlight the need for improved hygiene practices and routine screening for HEV, especially in healthcare settings. Further research is recommended to better understand HEV epidemiology in Nigeria.

Keywords

Hepatitis E virus, Seroprevalence, Federal Medical Centre Mubi, Viral hepatitis, Public health, Nigeria.

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References

1. Abravanel, F., Chapuy-Regaud, S., Lhomme, S., Dubois, M., Peron, J. M., Alric, L., Izopet, J. (2020). Performance of two commercial assays for detecting hepatitis E virus RNA in acute or chronic infections. Journal of clinical Microbiology, 51(6), 1913-1916. [Google Scholar] [Crossref]

2. Aggarwal, R., Gandhi, S. (2020). The global prevalence of hepatitis E virus infection and susceptibility: a systematic review. Geneva: World Health Organization. [Google Scholar] [Crossref]

3. Kaba, H. Richet, I. Ravaux, J. Moreau, I. Poizot-Mar- tin, A. Motte et al., (2022) “Hepatitis E Virus Infection in Pa- tients Infected with the Human Immunodeficiency Virus,” Journal of Medical Virology, Vol. 83, No. 10, pp. 1704-1716. [Google Scholar] [Crossref]

4. Kamar, N., Selves, J., Mansuy, J. M., Ouezzani, L., Péron, J. M., Guitard, J., Rostaing, L. (2008). Hepatitis E virus and chronic hepatitis in organ- transplant recipients. New England Journal of Medicine, 358(8), 811-817. [Google Scholar] [Crossref]

5. Kumar, M., Sharma, B. C., Sarin, S. K. (2022). Hepatitis E virus as an etiology of acute exacerbation of previously unrecognized asymptomatic patients with hepatitis B virus‐related chronic liver disease. Journal of gastroenterology and hepatology, 23(6), 883-887. [Google Scholar] [Crossref]

6. Labrique, A. B; Zaman, K.; Hossain, Z. Saha, P; Yunus, M. and Hossain, A. ( 2020) “Epidemiology and Risk Factors of In- cident Hepatitis E Virus Infections in Rural Bangladesh,” American Journal Epidemiology, Vol. 172, No. 8, pp. 952-961. [Google Scholar] [Crossref]

7. Mushahwar, I. K. (2008). Hepatitis E virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention. Journal of medical virology, 80(4), 646-658. [Google Scholar] [Crossref]

8. Navaneethan, U., Al Mohajer, M., Shata, M. T. (2008). Hepatitis E and pregnancy: understanding the pathogenesis. Liver international, 28(9), 1190-1199. [Google Scholar] [Crossref]

9. Omolade, S. O., Odaibo, G. N., Olaleye, O. D., Ayoola, E. A. (2022). Hepatitis B and E viral infection among Nigerian healthcare workers. [Google Scholar] [Crossref]

10. Osundare, F. A., Klink, P., Majer, C., Akanbi, O. A., Wang, B., Faber, M., Opaleye, O. O. (2020). Hepatitis E virus seroprevalence and associated risk factors in apparently healthy individuals from Osun State, Nigeria. Pathogens, 9(5), 392. [Google Scholar] [Crossref]

11. Purcell, R. H., Emerson, S. U. (2020). Hepatitis E: an emerging awareness of an old disease. Journal of hepatology, 48(3), 494-503. [Google Scholar] [Crossref]

12. Purdy, M. A., Harrison, T. J., Jameel, S., Meng, X. J., Okamoto, H., Van der Poel, W. H. M., Smith, D. B. Ictv Report C. (2017). ICTV virus taxonomy profile: Hepeviridae. Journal of General Virology, 98, 2645-2646. [Google Scholar] [Crossref]

13. Robson, S. Adams, N. Brink, B. Woodruff and D. Bradley, (2020). “Hospital Outbreak of Hepatitis E,” Lancet, Vol. 339, No. 8806, pp. 1424-1425 [Google Scholar] [Crossref]

14. Vasickova, P., Psikal, I., Widen, F., Smitalova, R., Bendova, J., Pavlik, I., Kralik, P. (2022). Detection and genetic characterisation of hepatitis E virus in Czech pig production herds. Research in veterinary science, 87(1), 143-148. [Google Scholar] [Crossref]

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