Polyherbal Extracts and its Potential Impact on Dandruff Causative Agent of Malassezia globosa
Authors
S. Sujatha
Assistant Professor, Department of Biotechnology, Malankara Catholic College, Mariagiri-629153 (IN)
Pivishni. V
B. Sc students, Department of Biotechnology, Malankara Catholic College Mariagiri-629153, Kaliyakkavilai, Tamilnadu. (IN)
Ann Ameesha. M
B. Sc students, Department of Biotechnology, Malankara Catholic College Mariagiri-629153, Kaliyakkavilai, Tamilnadu. (IN)
Sudeep Kumar. S
B. Sc students, Department of Biotechnology, Malankara Catholic College Mariagiri-629153, Kaliyakkavilai, Tamilnadu. (IN)
Priyadarshini. S
B. Sc students, Department of Biotechnology, Malankara Catholic College Mariagiri-629153, Kaliyakkavilai, Tamilnadu. (IN)
Article Information
DOI: 10.51583/IJLTEMAS.2026.150500138
Subject Category: Biotechnology
Volume/Issue: 15/5 | Page No: 1768-1778
Publication Timeline
Submitted: 2026-06-09
Published: 2026-06-09
Abstract
At present, more than quasi of the worldwide people deal with the major skin problem with dandruff. The presence of the Malassezia fungus suggestively subsidizes this condition by potentially generating the production of cytokines in keratinocytes, the cells responsible for synthesizing keratin and activating provocative alleyways. Antifungal activity of selected Indian medicinal plant extracts against the dandruff causing pathogen. The present work assigned the four experimental plants named Eclipta alba, Hibiscus rosasinensis, Lawsonia inermis and Muraya koenigii and its polyherbal mixed composition of these four herbal extracts. The prepared aqueous poly herbal extracts were added to the wells of Malassezia globossa inoculated plates. From the present antifungal result was clearly expressed all the four individual plant extract showed minimum to maximum antidandruff activity among the four M.koeningi possessed maximum antifungal activity than other three extracts. Even though, a mixed composition of these four herbal extracts (aqueous) contains the maximum potential antidandruff effect than the individual extracts of E.alba, H. rosasinensis, L. inermis. Hence, the present experimental four herbal extract was definitely depicted for great potential against the dandruff and skin pathogenic fungal organism of M. globossa.
Keywords
Herbal Extract, M.globossa, Eclipta alba, Hibiscus rosasinensis, Lawsonia inermis and Muraya koenigii.
Downloads
References
1. Abhijeet pandey, Jui V. Jagpat, S. A. ,2011. Polshettiwar. “Formulation and Evaluation of in-vitro Antimicrobial activity of gel containing essential oils and effect of polymer on their antimicrobial activity” International Journal of Pharmacy and Pharmaceutical Sciences. vol3: 1, pg: 234-237. [Google Scholar] [Crossref]
2. Ahonsi, C.O, Ovobovwori, S.U. and Etatuvie, S.O. 2023. Phytochemical and Antioxidant Activities of a Polyherbal Formulation from Selected Medicinal Herbs. IJCMCR. 25(5):01-08. [Google Scholar] [Crossref]
3. Al Nasr, I. Jentzsch, J. Winter, I. Schobert, R. Ersfeld, K. Koko, W. S. Mujawah, A. A Khan, T. A.and Biersack, B. 2019. Antiparasitic Activities of New Lawsone Mannich Bases. Arch. Pharm. (Weinheim), 552 (11), 1900128. [Google Scholar] [Crossref]
4. Almeida, P. J., Borrego, L., Pulido-Melián, E., and González-Díaz, O. 2012. Quantification of Phenylenediamine and 2-Hydroxy-1,4- Naphthoquinone in Henna Tattoos. Contact Dermatitis, 66 (1), 33-37. [Google Scholar] [Crossref]
5. Amat-ur-Rasool, H. Symes, F. Tooth, D. Schaffert, L. N Elmorsy, E. Ahmed, M Hasnain, S. Carter, W. G.2020. Potential Nutraceutical Properties of Leaves from Several Commonly Cultivated Plants. Biomolecules, 10 (11), 1556. [Google Scholar] [Crossref]
6. Arora P., Nanda A. and Karan M. 2011. Plants used in management of Dandruff”. The Indian Pharmacist. March, pg: 28-31. [Google Scholar] [Crossref]
7. Arora pooja, Nanda Arun, Karan M. 2013, “Screening of plant essential oils for antifungal activity against malassezia furfur” Int.journal of pharmacy & pharmaceutical sciences. Vol.5, issue2, 37-39 [Google Scholar] [Crossref]
8. Ayhan M, Sancak B, Karaduman A, Arikan S, Sahin S. 2007. Colonization of neonate skin by Malassezia species: relationship with neonatal cephalic pustulosis. J Am Acad Dermatol.; 57(6):1012–8. [Google Scholar] [Crossref]
9. Clayton T. Shaw, Raymond W. Vanderwyk 1967. “The Human Scalp as a Habitat for Molds”. J.Soc.Cosmetic Chemists. 18(): 563-568. [Google Scholar] [Crossref]
10. Diana P., Nandita K. and Padma T. 2015. Hibiscus Rosa Sinensis -a versatile Indian origin plant. J . Chem Pharma Sci, 8(4): 567-79. [Google Scholar] [Crossref]
11. Diana Pearline, Nandita Kamat, and Padma Thiagarajan. 2015. Hibiscus Rosa Sinensis -a versatile Indian origin plant. J Chem Pharma Sci, 8(4): 567-79. [Google Scholar] [Crossref]
12. Dikshit A, Tiwari A.K, Mishra R.K, Kamra A, Pandey A, Kumar A, and Bajaj A.K. 2012. Medicinal Plants, 4 (2): 55-64. [Google Scholar] [Crossref]
13. Gholve S, Nadarge S, Hindole S, Bhusnure O, Bhosale P, Thonte S. 2015. Formulation and Evaluation Of Polyherbal Antidandruff Powder Shampoo. World J Pharma Res, 4 (10): 1714-31. [Google Scholar] [Crossref]
14. Jahan R, Al-Nahain A, Majumder S, Rahmatullah M. 2014. Ethnopharmacological significance of Eclipta alba (L.) Hassk. (Asteraceae). Int Sch Res Notices; 2014385969. [Google Scholar] [Crossref]
15. Jordão A.K, Vargas M.D, Pinto A.C, da Silva F.D, Ferreira V.F. 2015. Lawsone in organic synthesis. RSC Adv., 5 (83),67909-67943. [Google Scholar] [Crossref]
16. Khare C.P, 2004. Encyclopedia of Indian Medicinal Plants, Springer-verlag Berlin Heidelberg, New York, 197- 198. [Google Scholar] [Crossref]
17. Kumar G.S, Jayaveera, K.N, Ashok kumar C.K, Umachigi Sanjay, Vrushabendra Swamy B.M, 2007Kishore Kumar.. Tropical J Pharm Res;6 (2) :717-723. [Google Scholar] [Crossref]
18. Lee, Jeong-Hyun and Jae-Sug Lee. 2010. Chemical composition and Antifungal Activity of Plant Essential Oils Against Malassezia furfur” Kor. J. Microbiol. Biotechnol. 38: 3, 315-321. [Google Scholar] [Crossref]
19. Naveen S, Karthika S, Sentila R, Mahenthiran R, Michael A. 2012. In-vitro evaluation of herbal and chemical agents in the management of dandruff; 2 (6):916-921. [Google Scholar] [Crossref]
20. Piepard, J. E. Arrese, C. Pierard Franchimont, P. De Doncker 1997. Prolonged effects of antidandruff shampoos – time to recurrence of Malassezia ovalis colonization of skin”. Int J Cosmet Sci. 3: 111-117. [Google Scholar] [Crossref]
21. Rashmi S. Pal Open Modal D Nikita Saraswat1 Pranay Wal Ankita Wal and Yogendra Pal. 2017. Preparation & Assessment of Poly-Herbal Anti-Dandruff Formulation, [Google Scholar] [Crossref]
22. TODJ-14-22 [Google Scholar] [Crossref]
23. Ronald R. Warner, James R, Schwartz, Ying Boissy BS, and L Dawson Jr, Ross, Ohio. 2001. American academy of dermatology;45 (6):897-903. [Google Scholar] [Crossref]
24. Roy RK, Thakur M, Dixit V.K, 2008. Arch Dermatology Res, 300(7), 357-364 [Google Scholar] [Crossref]
25. Sanflippo A. 2006, An overview of medicated shampoos used in dandruff treatment J Ethnopharmacol, 31(7):396-400. [Google Scholar] [Crossref]
26. Singla chhavi, Drabu Sushma and Ali Mohammad 2011. “Potential of herbals as antidandruff agents”. International Research journal of Pharmacy. 2: 3, pg:16-18. [Google Scholar] [Crossref]
27. Uma Agarwal, Prajakta S Pande, Pralhad S Patki, Mitra SK. 2009. Evaluation of the c linical efficacy and safety of "hair cream for dandruff"in the treatment of dandruff granted specifically for"the antiseptic”.:106 (1):37-39. [Google Scholar] [Crossref]
28. Vijayakumar R., C. Muthukumar, T. Kumar, R. Saravanamuthu 2006. “Characterization of Malassezia furfur and its control by using plant extracts”. Indian Journal of Dematology. vol 51 2, 2006 145-148. [Google Scholar] [Crossref]
29. Wagner H, Geyer B, 1986 . Coumestans as the main active principles of the liver drugs Eclipta alba an`d Wedelia calendulaceae, Planta Med, , 52:370-374. [Google Scholar] [Crossref]
30. Yu J.Y, Gupta B, Park, H.G, 2017. Preclinical and Clinical Studies Demonstrate That the Proprietary Herbal Extract DA-5512 Effectively Stimulates Hair Growth and Promotes Hair Health. Evid Based Complement Alternat Med, 20174395638. [Google Scholar] [Crossref]
Metrics
Views & Downloads
Similar Articles
- Block-Based Programming for Education: A Comprehensive Analysis of Visual Programming Environments in K-12 Learning
- Management of Academic Libraries and Client Satisfaction Towards Digital Utilization: Basis for Monitoring Library Operations in SOCCSKSARGEN Region.
- Revenue Leakages in TPA Insurance Claims and Corporate Claims: An Institutional Overview of Aster Prime Hospital, Hyderabad
- Technology and Innovation in Hospitality and Tourism: A Management Perspective
- Geospatial Distribution of Tarok Sacred Grove of Langtang North and Langtang South Local Government Areas