Therapeutic Applications of Nigella Sativa in Fungal Acne and Dermatological Infections: A Review

Abstract: This study explores the therapeutic potential of Nigella sativa (Black Seed) and its bioactive compounds in treating various skin conditions, particularly fungal infections. Fungal skin diseases, caused by pathogens like Malassezia and Candida, are increasingly prevalent and often challenging to manage. The paper delves into the pharmacological properties of Nigella sativa, focusing on its antimicrobial, antifungal, and anti-inflammatory effects. The study also reviews its role in managing acne vulgaris, fungal acne, and other dermatological disorders. Additionally, the paper examines the skin microbiome's impact on these conditions and the synergistic effects of Nigella sativa’s components with conventional treatments. The findings highlight the promising therapeutic applications of Nigella sativa, particularly its bioactive compound thymoquinone, in addressing skin infections and improving skin health. This research contributes to the growing body of knowledge on alternative treatments for skin diseases, suggesting Nigella sativa as a valuable adjunct in dermatological care.

Fungal acne, Nigella sativa, Acne pathogenesis, Dermatology, Acne treatment

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