Varicose Vein Sclerotherapy Using Polidocanol for Chronic Non-Healing Leg Ulcer: A Case Report from Muhimbili National Hospital
Authors
Azza Naif, MMed
Interventional Radiologist Department of Radiology, Muhimbili National Hospital Dar es Salaam, Tanzania (TZ)
Wesley D. Oliver, B.S.
Medical Student Howard University College of Medicine (TZ)
Erick Mbuguje, MMed
Interventional Radiologist Department of Radiology, Muhimbili National Hospital Dar es Salaam, Tanzania (TZ)
Shemin Mehta, MBChB
Consultant Interventional Radiologist Liverpool University Hospitals NHS Foundation Trust Liverpool, United Kingdom (TZ)
Mwivano Shemweta, MMed
Interventional Radiologist Department of Radiology, Muhimbili National Hospital Dar es Salaam, Tanzania (NG)
Article Information
DOI: 10.51583/IJLTEMAS.2026.150600272
Subject Category: Varicose Vein
Volume/Issue: 15/6 | Page No: 3693-3699
Publication Timeline
Submitted: 2026-08-03
Published: 2026-08-03
Abstract
Background: Chronic venous ulcers represent the most severe manifestation of chronic venous insufficiency and are associated with significant morbidity, particularly when longstanding and untreated. In low-resource settings, limited access to advanced vascular interventions often results in prolonged disease duration and poor outcomes. Minimally invasive techniques such as ultrasound-guided foam sclerotherapy offer a potential alternative for definitive management.
Case Presentation: We report a 26-year-old male who presented with a 10-year history of left lower limb swelling and a chronic non-healing ulcer around the ankle. The lesion initially developed as a raised skin lesion and progressed into an ulcer associated with intermittent bleeding. Clinical examination revealed varicose veins and localized swelling of the left lower limb. Duplex ultrasound demonstrated dilatation of the small saphenous vein with an incompetent sapheno-popliteal junction and multiple incompetent perforator veins, with no evidence of deep venous thrombosis.
Intervention: The patient underwent ultrasound-guided polidocanol foam sclerotherapy targeting the incompetent venous segments.
Outcome: Following treatment, progressive ulcer healing was observed, culminating in complete epithelialization and resolution of symptoms. No complications were reported.
Conclusion: This case demonstrates that ultrasound-guided polidocanol foam sclerotherapy can achieve complete healing of longstanding venous ulcers by addressing underlying venous reflux. It also highlights the feasibility and effectiveness of this minimally invasive technique in a low-resource setting and supports its broader adoption in similar healthcare environments.
Keywords
Chronic venous ulcer, polidocanol, foam sclerotherapy, interventional radiology, Tanzania, venous insufficiency
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References
1. O'Donnell, T. F., Jr, Passman, M. A., Marston, W. A., Ennis, W. J., Dalsing, M., Kistner, R. L., Lurie, F., Henke, P. K., Gloviczki, M. L., Eklöf, B. G., Stoughton, J., Raju, S., Shortell, C. K., Raffetto, J. D., Partsch, H., Pounds, L. C., Cummings, M. E., Gillespie, D. L., McLafferty, R. B., Murad, M. H., … American Venous Forum (2014). Management of venous leg ulcers: clinical practice guidelines of the Society for Vascular Surgery ® and the American Venous Forum. Journal of vascular surgery, 60(2 Suppl), 3S–59S. https://doi.org/10.1016/j.jvs.2014.04.049 [Google Scholar] [Crossref]
2. Rochon, P. J., Reghunathan, A., Kapoor, B. S., Kalva, S. P., Fidelman, N., Majdalany, B. S., Abujudeh, H., Caplin, D. M., Eldrup-Jorgensen, J., Farsad, K., Guimaraes, M. S., Gupta, A., Higgins, M., Kendi, A. T., Khilnani, N. M., Patel, P. J., Dill, K. E., & Hohenwalter, E. J. (2023). ACR Appropriateness Criteria® Lower extremity chronic venous disease. Journal of the American College of Radiology, 20(11), S481–S500. https://doi.org/10.1016/j.jacr.2023.08.011 [Google Scholar] [Crossref]
3. Probst, S., Saini, C., Gschwind, G., Stefanelli, A., Bobbink, P., Pugliese, M. T., Cekic, S., Pastor, D., & Gethin, G. (2023). Prevalence and incidence of venous leg ulcers-A systematic review and meta-analysis. International Wound Journal, 20(9), 3906–3921. https://doi.org/10.1111/iwj.14272 [Google Scholar] [Crossref]
4. Weber, B., Marquart, E., Deinsberger, J., Tzaneva, S., & Böhler, K. (2022). Comparative analysis of endovenous laser ablation versus ultrasound-guided foam sclerotherapy for the treatment of venous leg ulcers. Dermatologic therapy, 35(4), e15322. https://doi.org/10.1111/dth.15322 [Google Scholar] [Crossref]
5. Campos, W., Jr, Torres, I. O., da Silva, E. S., Casella, I. B., & Puech-Leão, P. (2015). A prospective randomized study comparing polidocanol foam sclerotherapy with surgical treatment of patients with primary chronic venous insufficiency and ulcer. Annals of vascular surgery, 29(6), 1128–1135. https://doi.org/10.1016/j.avsg.2015.01.031 [Google Scholar] [Crossref]
6. Hamel-Desnos, C., Desnos, P., Wollmann, J. C., Ouvry, P., Mako, S., & Allaert, F. A. (2003). Evaluation of the efficacy of polidocanol in the form of foam compared with liquid form in sclerotherapy of the greater saphenous vein: initial results. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 29(12), 1170–1175. https://doi.org/10.1111/j.1524-4725.2003.29398. [Google Scholar] [Crossref]
7. Ouvry, P., Allaert, F. A., Desnos, P., & Hamel-Desnos, C. (2008). Efficacy of polidocanol foam versus liquid in sclerotherapy of the great saphenous vein: a multicentre randomised controlled trial with a 2-year follow-up. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 36(3), 366–370. https://doi.org/10.1016/j.ejvs.2008.04.010 [Google Scholar] [Crossref]
8. Campos, W., Torres, I. O., Da Silva, E. S., Casella, I. B., & Puech-Leão, P. (2015). A Prospective Randomized Study Comparing Polidocanol Foam Sclerotherapy with Surgical Treatment of Patients with Primary Chronic Venous Insufficiency and Ulcer. Annals of Vascular Surgery, 29(6), 1128–1135. https://doi.org/10.1016/j.avsg.2015.01.031 [Google Scholar] [Crossref]
9. O'Hare, J. L., & Earnshaw, J. J. (2010). Randomised clinical trial of foam sclerotherapy for patients with a venous leg ulcer. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 39(4), 495–499. https://doi.org/10.1016/j.ejvs.2009.11.025 [Google Scholar] [Crossref]
10. Bacelar, A. C. C., Netto, E. M., Barreto, N., Neves, R., Heine, C., Botelho, P., Almeida, C. S., Ramalho, E., & Aras, R. (2025). Promising results of ultrasound guided foam sclerotherapy for treating chronic venous ulcers. Journal of vascular surgery. Venous and lymphatic disorders, 13(3), 102198. https://doi.org/10.1016/j.jvsv.2025.102198 [Google Scholar] [Crossref]
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