Varicose Vein Sclerotherapy Using Polidocanol for Chronic Non-Healing Leg Ulcer: A Case Report from Muhimbili National Hospital

Article Sidebar

Main Article Content

Azza Naif, MMed
Wesley D. Oliver, B.S.
Erick Mbuguje, MMed
Shemin Mehta, MBChB
Mwivano Shemweta, MMed

Background: Chronic venous ulcers represent the most severe manifestation of chronic venous insufficiency and are associated with significant morbidity, particularly when longstanding and untreated. In low-resource settings, limited access to advanced vascular interventions often results in prolonged disease duration and poor outcomes. Minimally invasive techniques such as ultrasound-guided foam sclerotherapy offer a potential alternative for definitive management.


Case Presentation: We report a 26-year-old male who presented with a 10-year history of left lower limb swelling and a chronic non-healing ulcer around the ankle. The lesion initially developed as a raised skin lesion and progressed into an ulcer associated with intermittent bleeding. Clinical examination revealed varicose veins and localized swelling of the left lower limb. Duplex ultrasound demonstrated dilatation of the small saphenous vein with an incompetent sapheno-popliteal junction and multiple incompetent perforator veins, with no evidence of deep venous thrombosis.


Intervention: The patient underwent ultrasound-guided polidocanol foam sclerotherapy targeting the incompetent venous segments.


Outcome: Following treatment, progressive ulcer healing was observed, culminating in complete epithelialization and resolution of symptoms. No complications were reported.


Conclusion: This case demonstrates that ultrasound-guided polidocanol foam sclerotherapy can achieve complete healing of longstanding venous ulcers by addressing underlying venous reflux. It also highlights the feasibility and effectiveness of this minimally invasive technique in a low-resource setting and supports its broader adoption in similar healthcare environments.

Varicose Vein Sclerotherapy Using Polidocanol for Chronic Non-Healing Leg Ulcer: A Case Report from Muhimbili National Hospital. (2026). International Journal of Latest Technology in Engineering Management & Applied Science, 15(6), 3693-3699. https://doi.org/10.51583/IJLTEMAS.2026.150600272

Downloads

References

O'Donnell, T. F., Jr, Passman, M. A., Marston, W. A., Ennis, W. J., Dalsing, M., Kistner, R. L., Lurie, F., Henke, P. K., Gloviczki, M. L., Eklöf, B. G., Stoughton, J., Raju, S., Shortell, C. K., Raffetto, J. D., Partsch, H., Pounds, L. C., Cummings, M. E., Gillespie, D. L., McLafferty, R. B., Murad, M. H., … American Venous Forum (2014). Management of venous leg ulcers: clinical practice guidelines of the Society for Vascular Surgery ® and the American Venous Forum. Journal of vascular surgery, 60(2 Suppl), 3S–59S. https://doi.org/10.1016/j.jvs.2014.04.049

Rochon, P. J., Reghunathan, A., Kapoor, B. S., Kalva, S. P., Fidelman, N., Majdalany, B. S., Abujudeh, H., Caplin, D. M., Eldrup-Jorgensen, J., Farsad, K., Guimaraes, M. S., Gupta, A., Higgins, M., Kendi, A. T., Khilnani, N. M., Patel, P. J., Dill, K. E., & Hohenwalter, E. J. (2023). ACR Appropriateness Criteria® Lower extremity chronic venous disease. Journal of the American College of Radiology, 20(11), S481–S500. https://doi.org/10.1016/j.jacr.2023.08.011

Probst, S., Saini, C., Gschwind, G., Stefanelli, A., Bobbink, P., Pugliese, M. T., Cekic, S., Pastor, D., & Gethin, G. (2023). Prevalence and incidence of venous leg ulcers-A systematic review and meta-analysis. International Wound Journal, 20(9), 3906–3921. https://doi.org/10.1111/iwj.14272

Weber, B., Marquart, E., Deinsberger, J., Tzaneva, S., & Böhler, K. (2022). Comparative analysis of endovenous laser ablation versus ultrasound-guided foam sclerotherapy for the treatment of venous leg ulcers. Dermatologic therapy, 35(4), e15322. https://doi.org/10.1111/dth.15322

Campos, W., Jr, Torres, I. O., da Silva, E. S., Casella, I. B., & Puech-Leão, P. (2015). A prospective randomized study comparing polidocanol foam sclerotherapy with surgical treatment of patients with primary chronic venous insufficiency and ulcer. Annals of vascular surgery, 29(6), 1128–1135. https://doi.org/10.1016/j.avsg.2015.01.031

Hamel-Desnos, C., Desnos, P., Wollmann, J. C., Ouvry, P., Mako, S., & Allaert, F. A. (2003). Evaluation of the efficacy of polidocanol in the form of foam compared with liquid form in sclerotherapy of the greater saphenous vein: initial results. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 29(12), 1170–1175. https://doi.org/10.1111/j.1524-4725.2003.29398.

Ouvry, P., Allaert, F. A., Desnos, P., & Hamel-Desnos, C. (2008). Efficacy of polidocanol foam versus liquid in sclerotherapy of the great saphenous vein: a multicentre randomised controlled trial with a 2-year follow-up. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 36(3), 366–370. https://doi.org/10.1016/j.ejvs.2008.04.010

Campos, W., Torres, I. O., Da Silva, E. S., Casella, I. B., & Puech-Leão, P. (2015). A Prospective Randomized Study Comparing Polidocanol Foam Sclerotherapy with Surgical Treatment of Patients with Primary Chronic Venous Insufficiency and Ulcer. Annals of Vascular Surgery, 29(6), 1128–1135. https://doi.org/10.1016/j.avsg.2015.01.031

O'Hare, J. L., & Earnshaw, J. J. (2010). Randomised clinical trial of foam sclerotherapy for patients with a venous leg ulcer. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 39(4), 495–499. https://doi.org/10.1016/j.ejvs.2009.11.025

Bacelar, A. C. C., Netto, E. M., Barreto, N., Neves, R., Heine, C., Botelho, P., Almeida, C. S., Ramalho, E., & Aras, R. (2025). Promising results of ultrasound guided foam sclerotherapy for treating chronic venous ulcers. Journal of vascular surgery. Venous and lymphatic disorders, 13(3), 102198. https://doi.org/10.1016/j.jvsv.2025.102198

Article Details

How to Cite

Varicose Vein Sclerotherapy Using Polidocanol for Chronic Non-Healing Leg Ulcer: A Case Report from Muhimbili National Hospital. (2026). International Journal of Latest Technology in Engineering Management & Applied Science, 15(6), 3693-3699. https://doi.org/10.51583/IJLTEMAS.2026.150600272