Preliminary Evaluation of Kanchnar Shunti Ghanavati in Primary Hypothyroidism: A 12-Week Pilot Study

Abstract Primary hypothyroidism is a common endocrine disorder resulting from insufficient thyroid hormone production, causing fatigue, weight gain, and cold intolerance. In Ayurveda, it is associated with Kapha dosha and Meda dhatu imbalance, leading to sluggish metabolism. Kanchnar Shunti Ghanavati, combining Kanchnar (Bauhinia variegata) and Shunti (Zingiber officinale) in a concentrated tablet form, is traditionally used for Kapha balancing and thyroid support. This open-label pilot study evaluated its preliminary efficacy and safety in 10 patients with primary hypothyroidism over 12 weeks. Patients received 500 mg twice daily. Key outcomes included changes in thyroid-stimulating hormone (TSH), free thyroxine (FT4), symptom scores, and adverse events. Mean TSH decreased from 8.2 mIU/L to 4.5 mIU/L, FT4 increased from 0.7 to 1.1 ng/dL, and symptoms like fatigue improved by 45%. Mean body weight reduced by 2.3 kg. No serious adverse events occurred. These findings suggest potential benefits of Kanchnar Shunti Ghanavati, warranting larger controlled trials.

Ayurveda

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