Biogenic Nanoparticle Synthesis Using Ganoderma Macrofungi and Its Biomedical and Environmental Applications
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Ganoderma is a notable Indian conventional mushroom utilized in different ethnomedicinal practices. New advancements connected with this mushroom and their exercises are consistently reported. A few researchers working with spores of this therapeutic mushroom however data of this species are still limited. This review describes about the main advances for the extraction of biocomponents and their pharmacological and cell protective effects on health system because of their importance in drug discovery. Recognizing the bioavailability of the naturally dynamic parts of G. lucidum after oral administration, and very little has been published in this area. Although single compounds can mediate a biological effect, nutraceuticals often act through the synergistic activity of multiple metabolites. It is significant to gain a better understanding of the bioavailability of the active components in this mushroom under various conditions to ensure robust study designs and to maximise consumer advantage. Nanoparticles derived from macro fungi, including various mushroom species like Ganoderma spp. are well known to possess immune-modulatory, high nutritional, antimicrobial, antioxidant, and anticancerous effect. Fungi have intracellular metal uptake capacity and supreme wall binding ability. In this review also discussed the nanoparticles synthesis from micro fungi of Ganoderma species and mechanism of nanoparticles derived from the micro fungus.
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S. Zafar, S. Beg, S.K. Panda, M. Rahman, K.S. Alharbi, G.K. Jain, F.J. Ahmad, Novel therapeutic interventions in cancer treatment using protein and peptide-based targeted smart systems, Semin. Cancer Biol. 69 (2021) 249–267. https://doi.org/10.1016/j.semcancer.2019.08.023.
M.M. Al-Ansari, P. Dhasarathan, A.J.A. Ranjitsingh, L.A. Al-Humaid, Ganoderma lucidum inspired silver nanoparticles and its biomedical applications with special reference to drug resistant Escherichia coli isolates from CAUTI, Saudi J. Biol. Sci. 27 (2020) 2993–3002. https://doi.org/10.1016/j.sjbs.2020.09.008.
Y. Jing, J. Li, Y. Zhang, R. Zhang, Y. Zheng, B. Hu, L. Wu, D. Zhang, Structural characterization and biological activities of a novel polysaccharide from Glehnia littoralis and its application in preparation of nano-silver, Int. J. Biol. Macromol. 183 (2021) 1317–1326. https://doi.org/10.1016/j.ijbiomac.2021.04.178.
Y. Zhu, T.L. Tan, Penalized discriminant analysis for the detection of wild-grown and cultivated Ganoderma lucidum using Fourier transform infrared spectroscopy, Spectrochim. Acta - Part A Mol. Biomol. Spectrosc. 159 (2016) 68–77. https://doi.org/10.1016/j.saa.2016.01.018.
Y. Kan, T. Chen, Y. Wu, J. Wu, J. Wu, Antioxidant activity of polysaccharide extracted from Ganoderma lucidum using response surface methodology, Int. J. Biol. Macromol. 72 (2015) 151–157. https://doi.org/10.1016/j.ijbiomac.2014.07.056.
S. Zhang, G. Pang, C. Chen, J. Qin, H. Yu, Y. Liu, X. Zhang, Z. Song, J. Zhao, F. Wang, Y. Wang, L.W. Zhang, Effective cancer immunotherapy by Ganoderma lucidum polysaccharide-gold nanocomposites through dendritic cell activation and memory T cell response, Carbohydr. Polym. 205 (2019) 192–202. https://doi.org/10.1016/j.carbpol.2018.10.028.
S. Jogaiah, M. Kurjogi, M. Abdelrahman, N. Hanumanthappa, L.S.P. Tran, Ganoderma applanatum-mediated green synthesis of silver nanoparticles: Structural characterization, and in vitro and in vivo biomedical and agrochemical properties, Arab. J. Chem. 12 (2019) 1108–1120. https://doi.org/10.1016/j.arabjc.2017.12.002.
J. Si, Y. Wu, H.F. Ma, Y.J. Cao, Y.F. Sun, B.K. Cui, Selection of a pH- and temperature-stable laccase from Ganoderma australe and its application for bioremediation of textile dyes, J. Environ. Manage. 299 (2021). https://doi.org/10.1016/j.jenvman.2021.113619.
R. Nag, S. Nolan, V. O’Flaherty, O. Fenton, K.G. Richards, B.K. Markey, P. Whyte, D. Bolton, E. Cummins, Quantitative microbial human exposure model for faecal indicator bacteria and risk assessment of pathogenic Escherichia coli in surface runoff following application of dairy cattle slurry and co-digestate to grassland, J. Environ. Manage. 299 (2021) 113627. https://doi.org/10.1016/j.jenvman.2021.113627.
E. Rani, S.A. Mohshim, N.H. Yusof, M.Z. Ahmad, R. Goodacre, S.A. Alang Ahmad, L.S. Wong, Sensitive and selective detection of DNA fragments associated with Ganoderma boninense by DNA-nanoparticle conjugate hybridisation, J. Mater. Sci. 55 (2020) 14965–14979. https://doi.org/10.1007/s10853-020-05058-8.
A. Aygün, S. Özdemir, M. Gülcan, K. Cellat, F. Şen, Synthesis and characterization of Reishi mushroom-mediated green synthesis of silver nanoparticles for the biochemical applications, J. Pharm. Biomed. Anal. 178 (2020). https://doi.org/10.1016/j.jpba.2019.112970.
D. Zheng, J. Zhao, Y. Tao, J. Liu, L. Wang, J. He, J. Lei, K. Liu, pH and glutathione dual responsive nanoparticles based on Ganoderma lucidum polysaccharide for potential programmable release of three drugs, Chem. Eng. J. 389 (2020) 124418. https://doi.org/10.1016/j.cej.2020.124418.
X. Wang, X. Chen, Z. Qi, X. Liu, W. Li, S. Wang, A study of Ganoderma lucidum spores by FTIR microspectroscopy, Spectrochim. Acta - Part A Mol. Biomol. Spectrosc. 91 (2012) 285–289. https://doi.org/10.1016/j.saa.2012.02.004.
S.Y. Abdul-Hadi, M.N. Owaid, M.A. Rabeea, A. Abdul Aziz, M.S. Jameel, Rapid mycosynthesis and characterization of phenols-capped crystal gold nanoparticles from Ganoderma applanatum, Biocatal. Agric. Biotechnol. 27 (2020) 101683. https://doi.org/10.1016/j.bcab.2020.101683.
S.A. Fowotade, N.A. Yusof, J. Abdullah, Y. Sulaiman, S.F. Abd Rahman, Enhanced electrochemical sensing of secondary metabolites in oil palms for early detection of Ganoderma boninense, Sens. Bio-Sensing Res. 23 (2019) 100274. https://doi.org/10.1016/j.sbsr.2019.100274.
G. Krishna, V. Srileka, M.A. Singara Charya, E.S. Abu Serea, A.E. Shalan, Biogenic synthesis and cytotoxic effects of silver nanoparticles mediated by white rot fungi, Heliyon. 7 (2021) e06470. https://doi.org/10.1016/j.heliyon.2021.e06470.
T. Do Dat, N.D. Viet, N.M. Dat, P.L.T. My, D.B. Thinh, L.T.M. Thy, L.M. Huong, P.T. Khang, N.D. Hai, H.M. Nam, M.T. Phong, N.H. Hieu, Characterization and bioactivities of silver nanoparticles green synthesized from Vietnamese Ganoderma lucidum, Surfaces Interfaces. 27 (2021) 101453. https://doi.org/10.1016/j.surfin.2021.101453.
M. Al Harbi, A.A. Tayel, Synergistic in vitro anticancer actions of decorated selenium nanoparticles with fucoidan/Reishi extract against colorectal adenocarcinoma cells, (2022) 373–384.
H. Pan, Y. Wang, K. Na, Y. Wang, L. Wang, Z. Li, C. Guo, D. Guo, X. Wang, Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation, Cell Death Dis. 10 (2019). https://doi.org/10.1038/s41419-019-1653-7.
A. Isha, F.S. Akanbi, N.A. Yusof, R. Osman, W. Mui-Yun, S.N.A. Abdullah, NMR metabolomics approach for detection of Ganoderma boninense-infected oil palm leaves, J. Nanomater. 2019. https://doi.org/10.1155/2019/4729706.
V.P. Nguyen, H. Le Trung, T.H. Nguyen, D. Hoang, T.H. Tran, Synthesis of biogenic silver nanoparticles using Ganoderma lucidum extract and evaluation of theranostic applications, J. Nanomater. 2021. https://doi.org/10.1155/2021/6135920.
D. Sliva, Ganoderma lucidum (Reishi) in cancer treatment, Integr. Cancer Ther. 2 (2003) 358–364. https://doi.org/10.1177/1534735403259066.
H. Jiang, Y. Zhang, C. Wang, H. Wang, Recovery of hazardous microplastics through selective aluminum coating, J. Environ. Manage. 299 (2021) 113626.
M. Tawalbeh, A. Al-Othman, T. Salamah, Metal-based catalysts in pyrolysis of biomass, J. Environ. Manage. 299 (2021) 113597.
H. Yu, Y. Yang, T. Jiang, Ganoderma lucidum polysaccharide-conjugated nanoparticles for radiotherapy, ACS Appl. Mater. Interfaces. 11 (2019) 27536–27547.
V.P. Nguyen, H. Le Trung, Microwave-assisted biosynthesis of Au nanoparticles using Ganoderma lucidum, ACS Omega. 6 (2021) 32198–32207.
D. Yan, L. Li, Dioxins study in hazardous waste processing, J. Environ. Manage. 299 (2021) 113584.
M.A. Zolfagharipoor, A. Ahmadi, Agent-based groundwater modeling, J. Environ. Manage. 299 (2021) 113560.
M. Mohammadi, M. Gheibi, Bioremediation using fungal activities, J. Environ. Manage. 299 (2021) 113594.
K.S. Dunne, N.M. Holden, Phosphorus management in soils, J. Environ. Manage. 299 (2021) 113665.
A.P. Yunus, Y. Masago, Suspended solids analysis using MODIS imagery, J. Environ. Manage. 299 (2021) 113550.
M.A. Desai, A.S. Vedpathak, Electrochemical conversion studies, J. Environ. Manage. 299 (2021) 113564.
S. Sangkham, Detection of SARS-CoV-2 RNA in wastewater, J. Environ. Manage. 299 (2021) 113563.
D. Elumalai, T.Y. Suman, Gold nanoparticles using Ganoderma lucidum, Bull. Mater. Sci. 44 (2021).
Z. Tan, M.A. Koondhar, Air quality and energy consumption study, J. Environ. Manage. 299 (2021) 113572.
S. Wachtel-Galor, B. Tomlinson, Ganoderma lucidum biomarker responses, Br. J. Nutr. 91 (2004) 263–269.
C.R. Soccol, L.Y. Bissoqui, Pharmacological properties of Ganoderma lucidum spores, Int. J. Med. Mushrooms. 18 (2016) 757–767.
I.L. Tsai, C.Y. Tsai, PLGA nanoparticles with Lingzhi extracts, Exp. Eye Res. 206 (2021) 108539.
K.S. Bishop, C.H.J. Kao, Nutraceutical developments of Ganoderma lucidum, Phytochemistry. 114 (2015) 56–65.
T. Yang, F. Li, Pollutant emissions in cattle breeding, J. Environ. Manage. 299 (2021) 113615.
C. Wan, H. Li, Dicamba degradation using biochar, J. Environ. Manage. 299 (2021) 113602.
T. Söderqvist, S. Cole, Environmental compensation metrics, J. Environ. Manage. 299 (2021) 113622.
J. Wu, Z. Jiang, Microplastic contamination in water, J. Environ. Manage. 299 (2021) 113667.
X. Li, Y. Hou, Drug safety molecular design, J. Environ. Manage. 299 (2021) 113628.
F.N. Maluin, M.Z. Hussein, Chitosan nanoparticle fungicide system, Molecules. 24 (2019).
X. Lai, Y. Han, Platinum clusters using Ganoderma lucidum polysaccharide, Molecules. 26 (2021).
I.F. Mustafa, M.Z. Hussein, Hexaconazole nanodelivery system, Molecules. 26 (2021).
S. Zhang, W. Hu, Land supply-demand mismatch study, J. Environ. Manage. 299 (2021) 113605.
D. Skrzypczak, K. Mikula, Agricultural waste valorization, J. Environ. Manage. 299 (2021) 113480.
Q. Peng, R. Yang, Biodiversity conflict risk study, J. Environ. Manage. 299 (2021) 113449.
H. Kiriyama, H. Matsuda, Nitrogen stock in agriculture, J. Environ. Manage. 299 (2021) 113438.
Q. Huang, L. Li, Ganoderma polysaccharides immune enhancement, Nutrients. 11 (2019).
S. Heshmati, P. Makhdoumi, Microplastics in fish digestive system, J. Environ. Manage. 299 (2021) 113620.
Y.M. Dai, Y.Y. Li, Catalysts for biodiesel production, J. Environ. Manage. 299 (2021) 113592.
R. Kumar, A. Najda, Fungicide-loaded nanoparticles study, Polymers. 14 (2022).
C. Deng, D. Zhu, Water service supply-demand analysis, J. Environ. Manage. 299 (2021) 113660.
Z. Wang, T. Wu, Recycling electroplating sludge catalysts, J. Environ. Manage. 299 (2021) 113567.
X. Zhou, J. Lin, Ganodermataceae pharmacological functions, Am. J. Chin. Med. 35 (2007) 559–574.
J.W.M. Yuen, M.D.I. Gohel, Anticancer effects of Ganoderma lucidum, Nutr. Cancer. 53 (2005) 11–17.
S. Singh, K. Kuca, Nanoparticle effects on Ganoderma growth, Mycobiology. 48 (2020) 383–391.
D. Philip, Biosynthesis of nanoparticles using mushroom extract, Spectrochim. Acta. 73 (2009) 374–381.
Z. Molnár, V. Bódai, Green synthesis of gold nanoparticles by fungi, (2018).
J.L. Sharma, V. Dhayal, ZnO nanoparticles using fungi, 3 Biotech. 11 (2021).
S.C. Tudu, M. Zubko, CdS nanoparticles using mushroom extract, Appl. Phys. A. 127 (2021).
A. Ahmad, P. Mukherjee, Enzyme-mediated nanoparticle synthesis, J. Am. Chem. Soc. 124 (2002) 12108–12109.
A novel DNA nanosensor based on CdSe-ZnS quantum dots and Fe₃O₄ nanoparticles.
N. Li, Y.L. Hu, Ganoderma lucidum polysaccharide nanoparticles, J. Pharm. Pharmacol. 62 (2010) 139–144.
A. Umar, S. Ahmed, Laccase characterization from Ganoderma, Sci. Rep. 12 (2022).
M. Hu, W. Deng, Activated char briquettes adsorption study, J. Environ. Manage. 299 (2021) 113601.
J. Liu, R. Liu, Risk mitigation using Bayesian networks, J. Environ. Manage. 299 (2021) 113640.

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